Hans Nieper, MD was a well known innovator of Active Mineral Transport, the use of specific amino acid chelators to deliver minerals to specific sites in the body. He identified aspartate and orotate as active mineral transport chelators, providing unprecedented rates of mineral absorption and yielding unique therapeutic benefits.
Magnesium orotate is used by competitive athletes to increase endurance. It is also used to treat symptoms of magnesium deficiency including diabetes, hypertension, dementia, osteoporosis and to treat migraines, asthma, chronic lung disease, heart attacks, arrhythmias, blood vessel stiffness, atherosclerosis and high blood pressure.